This is a case of a 59 year-old female was seen due to pain and purulentdischarge on the right mandible. Patient is a diagnosed case of multiple myeloma three years prior to admission who was treated with melphalan, prednisone, zolendronic acid, and has undergone radiotherapy for 25 sessions. Panoramic radiograph of the mandibles showed radioluscency at the body of mandible suggestive of an osteonecrotic process. After discovering this, zolendronic acid was discontinued and sequestrectomy and hyperbaric oxygen was done as advised by the maxillofacial surgeon.
Leukemia is a dreaded cancer of the blood or bone marrow. An individual suffering from this disease has abnormal production of blood cells called leucocytes (white blood cells). The DNA of immature blood cells (typically white blood cells) gets damaged and causes cells to grow and divide abnormally. Under normal circumstances, blood cells do their work and die, and are replaced by new blood cells which are produced in the bone marrow. In abnormal situations, blood cells do not die easily and get accumulated, occupying more and more space. Consequently, there is less space for healthy blood cells which brings » » » [Read more]