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Understanding Sugar Substitutes And Their Role

Understanding Sugar Substitutes And Their Role image

Sugar substitutes are food additives that take the place of your regular table sugar, and are generally much sweeter. Usually helpful in weight management and diabetes, these substitutes also help fight tooth decay, and are effective in reactive hypoglycemia (drop in blood sugar level). Despite these advantages, sugar substitutes have many controversial questions that beg answers like whether their long term use affects health badly, how much of consumption is safe, and whether they really can function as real sugar replacements. A better understanding of sugar substitutes may help answer these questions. Common approved substitutes/sweeteners Aspartame – is 200 times » » » [Read more]

A Comparative Study of the Effect of Vildagliptin and Glimepiride on Glucose Variability in Type 2 Diabetic Patients With Inadequate Glycemic Control on Metformin

A Comparative Study of the Effect of Vildagliptin and Glimepiride on Glucose Variability in Type 2 Diabetic Patients With Inadequate Glycemic Control on Metformin image

Authors: Odessa G. Tolentino-Wilson, M.D., FPCP Augusto D. Litonjua, M.D., FPCP, FPSEM, FACE Section of Endocrinology and Metabolism Makati Medical Center INTRODUCTION: Vildagliptin is a member of the dipeptidyl peptidase IV inhibitor (DPP-IV inhibitor) class of drugs. These drugs are believed to improve glucose variability by restoring the physiologic pattern of insulin secretion. Vildagliptin improves glycemia by improving beta and alpha cells’ sensitivity to glucose.1 This addresses the impaired glucose-mediated suppression of glucagon secretion in diabetes that results in increased hepatic glucose output and subsequently hyperglycemia.2 In a study that compared the effect of vildagliptin and glimepiride on prandial glucagon » » » [Read more]