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The Burden Of Diabetes

The Burden Of Diabetes image

Once you are diagnosed with diabetes, you are a diabetic for life. That’s often said and it is true. Diabetes mellitus is a lifetime illness that involves high blood sugar levels which promotes complications if neglected. But it is not the high blood sugar level that kills you, it’s the complication. Hence, being a diabetic, one needs continuing medical care to achieve target blood sugar levels to prevent these complications. The burden of diabetes is steadily increasing globally. Because of rapid urbanization, change in nutrition brought about by the increasing popularity of fast food due to the busy lifestyle of » » » [Read more]

A Comparative Study of the Effect of Vildagliptin and Glimepiride on Glucose Variability in Type 2 Diabetic Patients With Inadequate Glycemic Control on Metformin

A Comparative Study of the Effect of Vildagliptin and Glimepiride on Glucose Variability in Type 2 Diabetic Patients With Inadequate Glycemic Control on Metformin image

Authors: Odessa G. Tolentino-Wilson, M.D., FPCP Augusto D. Litonjua, M.D., FPCP, FPSEM, FACE Section of Endocrinology and Metabolism Makati Medical Center INTRODUCTION: Vildagliptin is a member of the dipeptidyl peptidase IV inhibitor (DPP-IV inhibitor) class of drugs. These drugs are believed to improve glucose variability by restoring the physiologic pattern of insulin secretion. Vildagliptin improves glycemia by improving beta and alpha cells’ sensitivity to glucose.1 This addresses the impaired glucose-mediated suppression of glucagon secretion in diabetes that results in increased hepatic glucose output and subsequently hyperglycemia.2 In a study that compared the effect of vildagliptin and glimepiride on prandial glucagon » » » [Read more]